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Cover of The Antidote by Karen RussellThe Antidote
New · Fiction, Fantasy, LGBT

The Antidote

by Karen Russell
2025 · 628 pages · Fiction
Critics' pick
≈ 16 hours to read · about 5 weeks at 30 minutes a day

What it's about

Karen Russell's novel is a Dust Bowl epic about five characters in a small Nebraska town whose fates become entangled after a storm ravages it, written with her gift for the strange and the magical.

Why it's worth reading

It was a finalist for both the National Book Award and the National Book Critics Circle Award. Russell, a MacArthur Fellow, is one of the most imaginative American writers.

You'll love it if you liked

Good to know

It blends historical fiction with the supernatural.

By the numbers

68.4Must-Read Score
  • Readers34 out of 100 · counts 42%
  • Critics47 out of 100 · counts 34% (its stronger lane)
  • Bestseller13 out of 100 · counts 14%
  • Buzz72 out of 100 · counts 10%

Critics and Bestseller are two ways to earn a place: a book's stronger one counts more. Buzz rewards recent bestseller weeks and prizes, so older books start at zero. The parts combine into the Must-Read Score, shown on a scale where the best book we found scores 99 and the last book to make the ranking scores 50.

Where it ranks

Why it made the list

Shortlisted
National Book Award (Fiction) finalist (2025)NBCC Award (Fiction) finalist (2025)

Reads as

Epic

How we rank

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Explore the best-of lists

All 36 best-of lists →

Quick answers

Is The Antidote worth reading?

Yes. It was a finalist for both the National Book Award and the National Book Critics Circle Award. It ranks #1,481 of the 2,816 books in our ranking, with a Must-Read Score of 68.4 (the best book we found scores 99).

What is The Antidote about?

Karen Russell's novel is a Dust Bowl epic about five characters in a small Nebraska town whose fates become entangled after a storm ravages it, written with her gift for the strange and the magical.

How long does it take to read The Antidote?

About 16 hours (628 pages), or about 5 weeks at 30 minutes a day.

What should I read after The Antidote?

If you liked it, try The Grapes of Wrath by John Steinbeck, Lincoln in the Bardo by George Saunders or The Overstory by Richard Powers.